{"id":40617,"date":"2023-04-01T12:43:34","date_gmt":"2023-04-01T03:43:34","guid":{"rendered":"https:\/\/www.mcsg.co.jp\/kentatsu\/?p=40617"},"modified":"2023-05-10T21:25:32","modified_gmt":"2023-05-10T12:25:32","slug":"%e9%81%a9%e5%88%87%e3%81%aa%e7%9d%a1%e7%9c%a0%e3%81%a7%e3%80%81%e8%aa%8d%e7%9f%a5%e7%97%87%e3%81%8b%e3%82%89%e8%84%b3%e3%82%92%e5%ae%88%e3%82%8b","status":"publish","type":"post","link":"https:\/\/www.mcsg.co.jp\/kentatsu\/interview\/40617","title":{"rendered":"\u9069\u5207\u306a\u7761\u7720\u3067\u3001\u8a8d\u77e5\u75c7\u304b\u3089\u8133\u3092\u5b88\u308b"},"content":{"rendered":"<p style=\"text-align: center;\"><span style=\"font-weight: 400;\">\u91d1\u6ca2\u533b\u79d1\u5927\u5b66 \u9ad8\u9f62\u533b\u5b66\u79d1 \u81e8\u5e8a\u51c6\u6559\u6388<br \/>\n<\/span><span style=\"font-weight: 400;\">\u5c0f\u91ce\u592a\u8f14 \u5148\u751f<\/span><\/p>\n<p style=\"text-align: center;\"><span style=\"font-weight: 400;\">\u7b51\u6ce2\u5927\u5b66\u56fd\u969b\u7d71\u5408\u7761\u7720\u533b\u79d1\u5b66\u7814\u7a76\u6a5f\u69cb \u6559\u6388<br \/>\n<\/span><span style=\"font-weight: 400;\">\u795e\u6797\u5d07 \u5148\u751f<\/span><\/p>\n<h2><b>\u52a0\u9f62\u306b\u4f34\u3044\u3001\u7761\u7720\u306e\u8cea\u306f\u5909\u5316\u3059\u308b<\/b><\/h2>\n<p><span style=\"font-weight: 400;\">\u7761\u7720\u306f\u3001\u5927\u304d\u304f\u300c\u30ec\u30e0\u7761\u7720\u300d\u3068\u300c\u30ce\u30f3\u30ec\u30e0\u7761\u7720\u300d\u306e2\u3064\u306b\u5206\u3051\u3089\u308c\u307e\u3059\u3002<br \/>\n<\/span><\/p>\n<p><span style=\"font-weight: 400;\">\u30ec\u30e0\u7761\u7720\u6642\u306b\u306f\u5927\u8133\u304c\u6d3b\u767a\u306b\u50cd\u304d\u3001\u8a18\u61b6\u306e\u6574\u7406\u3084\u5b9a\u7740\u304c\u884c\u308f\u308c\u3066\u3044\u308b\u3068\u8003\u3048\u3089\u308c\u3066\u3044\u307e\u3059\u3002<br \/>\n\u4e00\u65b9\u3067\u3001\u30ce\u30f3\u30ec\u30e0\u7761\u7720\u6642\u306b\u306f\u5927\u8133\u306f\u4f11\u606f\u3057\u3066\u304a\u308a\u3001\u75b2\u52b4\u56de\u5fa9\u306e\u5f79\u5272\u3092\u62c5\u3063\u3066\u3044\u308b\u3068\u8003\u3048\u3089\u308c\u3066\u3044\u307e\u3059<\/span><span style=\"color: #cf2d2d;\"><strong>(*1 \u795e\u6797\u5d07\uff0c\u85e4\u539f\u6b63\u660e, 2021)<\/strong><\/span><span style=\"font-weight: 400;\">\u3002<\/span><\/p>\n<p><span style=\"font-weight: 400;\">\u53e4\u5178\u7684\u306b\u306f\u3001\u30ce\u30f3\u30ec\u30e0\u7761\u7720\u306fStage1\u304b\u3089Stage4\u306e4\u6bb5\u968e\u306b\u5206\u3051\u3089\u308c\u3001Stage1\u3068Stage2\u306f\u201c\u6d45\u3044\u201d\u30ce\u30f3\u30ec\u30e0\u7761\u7720\u3001Stage3\u3068Stage4\u306f\u201c\u6df1\u3044\u201d\u30ce\u30f3\u30ec\u30e0\u7761\u7720\u3068\u3055\u308c\u3066\u3044\u307e\u3059\u3002<br \/>\n\u6df1\u3044\u30ce\u30f3\u30ec\u30e0\u7761\u7720\u306f\u3001\u7761\u7720\u8133\u6ce2\u306e\u5468\u6ce2\u6570\u304c\u4f4e\u3044\u3053\u3068\u304b\u3089\u300c\u5f90\u6ce2\u7761\u7720\u300d\u3068\u547c\u3070\u308c\u307e\u3059\u3002<br \/>\n\u8fd1\u5e74\u3067\u306f\u3001\u3053\u306eStage3\u3068Stage4\u3092\u5f90\u6ce2\u7761\u7720\u6bb5\u968e\u3068\u3057\u3066\u4e00\u3064\u306b\u307e\u3068\u3081\u3001\u30ce\u30f3\u30ec\u30e0\u7761\u7720\u30923\u6bb5\u968e\u306b\u5206\u3051\u308b\u3053\u3068\u304c\u591a\u304f\u306a\u3063\u3066\u3044\u307e\u3059\u3002<\/span><\/p>\n<p><span style=\"font-weight: 400;\">\u52a0\u9f62\u306b\u4f34\u3044\u3001\u4e00\u822c\u7684\u306b\u306f\u4e0b\u8a18\u306e\u3088\u3046\u306b<\/span><\/p>\n<ul>\n<li><span style=\"font-weight: 400;\">\u2460\u5c31\u5e8a\u30fb\u96e2\u5e8a\u6642\u523b\u304c\u65e9\u304f\u306a\u308a\u3001<\/span><\/li>\n<li><span style=\"font-weight: 400;\">\u2461\u591c\u4e2d\u306b\u4f55\u5ea6\u3082\u76ee\u304c\u899a\u3081\u308b\u4e2d\u9014\u899a\u9192\u304c\u5897\u52a0\u3057\u3001<\/span><\/li>\n<li><span style=\"font-weight: 400;\">\u2462\u7dcf\u7761\u7720\u6642\u9593\u304c\u77ed\u7e2e\u3057\u3066\u7761\u7720\u52b9\u7387\uff08\u7dcf\u7761\u7720\u6642\u9593\u3092\u5c31\u5e8a\u6642\u9593\u3067\u5272\u3063\u305f\u5024\uff09<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">\u304c\u4f4e\u4e0b\u3059\u308b\u306a\u3069\u3001\u7761\u7720\u306e\u91cf\u7684\u30fb\u8cea\u7684\u306a\u4f4e\u4e0b\u304c\u751f\u3058\u308b\u3053\u3068\u304c\u77e5\u3089\u308c\u3066\u3044\u307e\u3059<\/span><span style=\"color: #cf2d2d;\"><strong>(*2 Mishima, 2015)<\/strong><\/span><span style=\"font-weight: 400;\">\u3002<\/span><\/p>\n<h3><b>\u2460\u5c31\u5e8a\u30fb\u96e2\u5e8a\u6642\u523b\u306e\u524d\u9032<\/b><\/h3>\n<p><span style=\"font-weight: 400;\">\u52a0\u9f62\u306b\u4f34\u3063\u3066\u5c11\u3057\u305a\u3064\u5bdd\u308b\u6642\u9593\u30fb\u8d77\u304d\u308b\u6642\u523b\u304c\u65e9\u304f\u306a\u308a\u3001\u3044\u308f\u3086\u308b\u65e9\u5bdd\u65e9\u8d77\u304d\u306b\u306a\u308a\u307e\u3059\u3002<\/span><\/p>\n<h3><b>\u2461\u4e2d\u9014\u899a\u9192\u306e\u5897\u52a0<\/b><\/h3>\n<p><span style=\"font-weight: 400;\">\u52a0\u9f62\u306b\u4f34\u3063\u3066\u5f90\u6ce2\u7761\u7720 (\u6df1\u3044\u30ce\u30f3\u30ec\u30e0\u7761\u7720) \u304c\u6e1b\u5c11\u3057\u3001\u7d50\u679c\u3068\u3057\u3066\u7761\u7720\u304c\u6d45\u304f\u306a\u308a\u3001\u4e2d\u9014\u899a\u9192\u304c\u307f\u3089\u308c\u308b\u3053\u3068\u304c\u591a\u304f\u306a\u308a\u307e\u3059\uff08<\/span><span style=\"color: #cf2d2d;\"><strong>\uff3b\u56f31\uff3d\uff3b\u56f32\uff3d<\/strong><\/span><span style=\"font-weight: 400;\">\u53c2\u7167\uff09\u3002<\/span><\/p>\n<p><span style=\"color: #cf2d2d;\"><b>\uff3b\u56f31\uff3d<\/b><\/span><span style=\"font-weight: 400;\">\u30ce\u30f3\u30ec\u30e0\u7761\u7720Stage1\u3001Stage2\u3001\u5f90\u6ce2\u7761\u7720\u3001\u30ec\u30e0\u7761\u7720\u3001\u4e2d\u9014\u899a\u9192\u3001\u304a\u3088\u3073\u5165\u7720\u6f5c\u6642\u306e\u5e74\u9f62\u306b\u95a2\u9023\u3059\u308b\u50be\u5411<\/span><span style=\"color: #cf2d2d;\"><strong>\uff08*3\u00a0 Ohayon et al., 2004\uff09<\/strong><\/span><\/p>\n<p><img decoding=\"async\" class=\"aligncenter wp-image-40648\" src=\"https:\/\/www.mcsg.co.jp\/kentatsu\/wp-content\/uploads\/2023\/03\/\u56f31.png\" alt=\"\" width=\"1552\" height=\"926\" \/><\/p>\n<p><span style=\"color: #cf2d2d;\"><b>\uff3b\u56f3\uff12\uff3d<\/b><\/span><span style=\"font-weight: 400;\">\u82e5\u5e74\u6210\u4eba\u304a\u3088\u3073\u9ad8\u9f62\u8005\u306e\u7761\u7720\u69cb\u9020<\/span><span style=\"color: #cf2d2d;\"><strong>\uff08*4\u00a0 Gulia and Kumar, 2018\uff09<\/strong><\/span><\/p>\n<p><img decoding=\"async\" class=\"aligncenter wp-image-40649\" src=\"https:\/\/www.mcsg.co.jp\/kentatsu\/wp-content\/uploads\/2023\/03\/\u56f32.png\" alt=\"\" width=\"1482\" height=\"914\" \/><\/p>\n<h3><b>\u2462\u7dcf\u7761\u7720\u6642\u9593\u306e\u77ed\u7e2e\u30fb\u7761\u7720\u52b9\u7387\u306e\u4f4e\u4e0b<\/b><\/h3>\n<p><span style=\"font-weight: 400;\">\u9ad8\u9f62\u8005\u306b\u304a\u3044\u3066\u306f\u3001\u4e00\u822c\u7684\u306b\u7761\u7720\u6642\u9593\u304c\u77ed\u7e2e\u3059\u308b\u4e00\u65b9\u3067\u3001\u5c31\u5e8a\u6642\u9593\u304c\u5ef6\u9577\u3059\u308b\u305f\u3081\u3001\u7761\u7720\u52b9\u7387\u306f\u4f4e\u4e0b\u3057\u307e\u3059\u3002<br \/>\n\u82e5\u5e74\u8005\u306e\u7761\u7720\u52b9\u7387\u304c\u901a\u5e3890\uff05\u3092\u8d85\u3048\u308b\u306e\u306b\u5bfe\u3057\u300165\u6b73\u4ee5\u4e0a\u306e\u9ad8\u9f62\u8005\u3067\u306f\u3001\u7761\u7720\u52b9\u7387\u304c80\uff05\u4ee5\u4e0b\u306b\u307e\u3067\u4f4e\u4e0b\u3059\u308b\u3053\u3068\u304c\u591a\u304f\u306a\u308a\u307e\u3059<\/span><span style=\"color: #cf2d2d;\"><strong>(*2 Mishima, 2015)<\/strong><\/span><span style=\"font-weight: 400;\">\u3002<\/span><\/p>\n<h2><b>\u7761\u7720\u4e0d\u8db3\u306f\u3001\u30a2\u30eb\u30c4\u30cf\u30a4\u30de\u30fc\u578b\u8a8d\u77e5\u75c7\u306e\u30ea\u30b9\u30af\u306b\u5f71\u97ff\u3059\u308b<\/b><\/h2>\n<p><span style=\"font-weight: 400;\">\u30a2\u30eb\u30c4\u30cf\u30a4\u30de\u30fc\u578b\u8a8d\u77e5\u75c7\u306f\u3001\u65e5\u672c\u3092\u542b\u3081\u3001\u4e16\u754c\u7684\u306b\u6700\u3082\u591a\u3044\u30bf\u30a4\u30d7\u306e\u8a8d\u77e5\u75c7\u3067\u3059\u3002<\/span><\/p>\n<p><span style=\"font-weight: 400;\">\u5178\u578b\u7684\u306b\u306f\u8a18\u9298\u529b\u969c\u5bb3\uff08\u65b0\u3057\u304f\u899a\u3048\u305f\u8a18\u61b6\u3092\u7dad\u6301\u3067\u304d\u306a\u3044\uff09\u304b\u3089\u767a\u75c7\u3057\u3001\u9032\u884c\u3068\u3068\u3082\u306b\u3001\u8a00\u8a9e\u6a5f\u80fd\u306e\u969c\u5bb3\u306a\u3069\u3082\u51fa\u73fe\u3057\u307e\u3059\u3002<br \/>\n\u3055\u3089\u306b\u9032\u884c\u3059\u308b\u3068\u3001\u88ab\u5bb3\u5984\u60f3\u3001\u8208\u596e\u3001\u663c\u591c\u9006\u8ee2\u3001\u305b\u3093\u5984\u3001\u5931\u7981\u3001\u5f98\u5f8a\u306a\u3069\u304c\u898b\u3089\u308c\u308b\u3088\u3046\u306b\u306a\u308a\u307e\u3059\u3002<\/span><\/p>\n<p><span style=\"font-weight: 400;\">\u306a\u305c\u30a2\u30eb\u30c4\u30cf\u30a4\u30de\u30fc\u578b\u8a8d\u77e5\u75c7\u306b\u306a\u308b\u306e\u304b\u3001\u305d\u306e\u539f\u56e0\u306f\u3044\u307e\u3060\u4e0d\u660e\u3067\u3059\u304c\u3001\u30a2\u30df\u30ed\u30a4\u30c9\u03b2<span style=\"color: #cf2d2d;\"><strong>\uff08\u30d9\u30fc\u30bf\uff09<\/strong><\/span>\u30bf\u30f3\u30d1\u30af\u8cea\u3084\u5fae\u5c0f\u7ba1\u7d50\u5408\u30bf\u30f3\u30d1\u30af\u8cea\uff08\u30bf\u30a6\uff09\u306a\u3069\u304c\u8133\u5185\u306b\u6c88\u7740\u3057\u3001\u8133\u795e\u7d4c\u7d30\u80de\u304c\u969c\u5bb3\u3055\u308c\u308b\u305f\u3081\u3068\u8003\u3048\u3089\u308c\u3066\u3044\u307e\u3059 (\u30a2\u30df\u30ed\u30a4\u30c9\u4eee\u8aac) \u3002<br \/>\n<\/span><span style=\"font-weight: 400;\">\u73fe\u6642\u70b9\u3067\u3001\u30a2\u30eb\u30c4\u30cf\u30a4\u30de\u30fc\u578b\u8a8d\u77e5\u75c7\u306e\u6839\u6cbb\u7642\u6cd5\u306f\u5b58\u5728\u305b\u305a\u3001\u30a2\u30df\u30ed\u30a4\u30c9\u4eee\u8aac\u306b\u57fa\u3065\u3044\u3066\u3001\u30a2\u30df\u30ed\u30a4\u30c9\u03b2\u304a\u3088\u3073\u30bf\u30a6\u304c\u8133\u5185\u306b\u6c88\u7740\u3059\u308b\u3053\u3068\u3092\u9632\u3050\u6cbb\u7642\u6cd5\u306e\u958b\u767a\u304c\u9032\u3081\u3089\u308c\u3066\u3044\u307e\u3059\u3002<\/span><\/p>\n<p><span style=\"font-weight: 400;\">\u305d\u3057\u3066\u5b9f\u306f\u3001\u3053\u306e\u30a2\u30df\u30ed\u30a4\u30c9\u03b2\u306f\u7761\u7720\u3068\u6df1\u3044\u95a2\u4fc2\u304c\u3042\u308a\u307e\u3059\u3002<br \/>\n\u30a2\u30df\u30ed\u30a4\u30c9\u03b2\u306e\u6fc3\u5ea6\u306f\u671d\u306b\u6700\u3082\u4f4e\u304f\u3001\u5915\u65b9\u304b\u3089\u591c\u306b\u304b\u3051\u3066\u30d4\u30fc\u30af\u3068\u306a\u308a\u307e\u3059<\/span><span style=\"color: #cf2d2d;\"><strong>(*5 Huang et al., 2012)<\/strong><\/span><span style=\"font-weight: 400;\">\u3002<br \/>\n\u3053\u306e\u3053\u3068\u304b\u3089\u3001\u7761\u7720\u4e2d\u306b\u8133\u5185\u306e\u30a2\u30df\u30ed\u30a4\u30c9\u03b2\u304c\u6392\u6cc4\u3055\u308c\u308b\u3068\u8003\u3048\u3089\u308c\u3066\u3044\u307e\u3059\u3002<br \/>\n<\/span><\/p>\n<p><span style=\"font-weight: 400;\">\u307e\u305f\u3001\u30a2\u30df\u30ed\u30a4\u30c9\u03b2\u306e\u6fc3\u5ea6\u306f\u7761\u7720\u6642\u9593\u3068\u3082\u95a2\u9023\u304c\u3042\u308a\u3001\u7761\u7720\u6642\u9593\uff08\u7279\u306b\u30ce\u30f3\u30ec\u30e0\u7761\u7720\uff09\u304c\u77ed\u304f\u306a\u308b\u307b\u3069\u3001\u30a2\u30df\u30ed\u30a4\u30c9\u03b2\u306e\u6fc3\u5ea6\u304c\u9ad8\u304f\u306a\u308a\u307e\u3059\u3002<br \/>\n\u3053\u306e\u3053\u3068\u304b\u3089\u3001\u7761\u7720\u4e0d\u8db3\u306f\u30a2\u30df\u30ed\u30a4\u30c9\u03b2\u306e\u6392\u6cc4\u3092\u4f4e\u4e0b\u3055\u305b\u3001\u30a2\u30df\u30ed\u30a4\u30c9\u03b2\u306e\u8133\u5185\u6c88\u7740\u3092\u5f15\u304d\u8d77\u3053\u3059\u3068\u8003\u3048\u3089\u308c\u3066\u3044\u307e\u3059\u3002<\/span><\/p>\n<h2><b>\u7761\u7720\u4e2d\u306e\u8133\u5185\u8001\u5ec3\u7269\u306e\u9664\u53bb\u306b\u3064\u3044\u3066\u3001\u65b0\u305f\u306a\u4eee\u8aac\u304c\u6ce8\u76ee\u3055\u308c\u3066\u3044\u308b<\/b><\/h2>\n<p><span style=\"font-weight: 400;\">\u8fd1\u5e74\u3001\u7761\u7720\u4e2d\u306b\u30a2\u30df\u30ed\u30a4\u30c9\u03b2\u306a\u3069\u306e\u8133\u5185\u8001\u5ec3\u7269\u3092\u6392\u6cc4\u3059\u308b\u65b9\u6cd5\u3068\u3057\u3066\u3001\u300c\u30b0\u30ea\u30f3\u30d1\u30c6\u30a3\u30c3\u30af\u30b7\u30b9\u30c6\u30e0\u4eee\u8aac\u300d\u304c\u63d0\u5531\u3055\u308c\u307e\u3057\u305f<\/span><span style=\"color: #cf2d2d;\"><strong>(*6\u00a0 Nedergaard, 2013)<\/strong><\/span><span style=\"font-weight: 400;\">\u3002<br \/>\n\u3053\u308c\u306f\u3001\u8133\u5185\u306e\u6db2\u4f53\u6210\u5206\u304c\u3001\u7761\u7720\u4e2d\u306b\u52d5\u8108\u304b\u3089\u9759\u8108\u306e\u65b9\u5411\u306b\u6d41\u308c\u3066\u8001\u5ec3\u7269\u3092\u62bc\u3057\u6d41\u3057\u3001\u8001\u5ec3\u7269\u3054\u3068\u9759\u8108\u306b\u56de\u53ce\u3055\u308c\u305f\u5f8c\u3001\u30ea\u30f3\u30d1\u7ba1\u304b\u3089\u6392\u6cc4\u3055\u308c\u308b\u3068\u3044\u3046\u3082\u306e\u3067\u3059\u3002<br \/>\n<\/span><\/p>\n<p><span style=\"font-weight: 400;\">\u8133\u795e\u7d4c\u7d30\u80de\u306f\u300c\u30b0\u30ea\u30a2\u300d\u3068\u3044\u3046\u7d30\u80de\u306b\u3088\u3063\u3066\u652f\u3048\u3089\u308c\u3066\u3044\u307e\u3059\u3002<br \/>\n\u7761\u7720\u4e2d\u306b\u3053\u306e\u30b0\u30ea\u30a2\u7d30\u80de\u306e\u9593\u9694\u304c\u5e83\u304c\u308b\u3053\u3068\u306b\u3088\u3063\u3066\u3001\u8133\u5185\u306e\u6db2\u4f53\u6210\u5206\u304c60\uff05\u307b\u3069\u5897\u52a0\u3057\u3001\u6d41\u308c\u308b\u91cf\u304c\u5897\u52a0\u3059\u308b\u3053\u3068\u3067\u3001\u8133\u5185\u306e\u30a2\u30df\u30ed\u30a4\u30c9\u03b2\u306a\u3069\u3092\u3088\u308a\u52b9\u7387\u7684\u306b\u6392\u6cc4\u3059\u308b\u3068\u3055\u308c\u3066\u3044\u307e\u3059 <\/span><span style=\"color: #cf2d2d;\"><strong>(*7 Xie et al., 2013)<\/strong><\/span><span style=\"font-weight: 400;\">\u3002<\/span><\/p>\n<p><span style=\"font-weight: 400;\">\u3053\u306e\u30b0\u30ea\u30f3\u30d1\u30c6\u30a3\u30c3\u30af\u30b7\u30b9\u30c6\u30e0\u306f\u3001\u30de\u30a6\u30b9\u306a\u3069\u306e\u9f67<span style=\"color: #cf2d2d;\"><strong>\uff08\u3052\u3063\uff09<\/strong><\/span>\u6b6f<span style=\"color: #cf2d2d;\"><strong>\uff08\u3057\uff09<\/strong><\/span>\u985e<span style=\"color: #cf2d2d;\"><strong>\uff08\u308b\u3044\uff09<\/strong><\/span>\u306b\u304a\u3044\u3066\u306f\u307b\u307c\u78ba\u5b9f\u306b\u5b58\u5728\u3059\u308b\u3068\u8003\u3048\u3089\u308c\u3066\u3044\u307e\u3059\u304c\u3001\u4eba\u9593\u306b\u304a\u3044\u3066\u3082\u540c\u69d8\u306e\u30b7\u30b9\u30c6\u30e0\u304c\u5b58\u5728\u3059\u308b\u306e\u304b\u306b\u3064\u3044\u3066\u306f\u3001\u660e\u3089\u304b\u306b\u306a\u3063\u3066\u3044\u307e\u305b\u3093\u3002<br \/>\n\u307e\u305f\u3001\u8133\u5185\u306e\u8001\u5ec3\u7269\u304c\u3069\u306e\u3088\u3046\u306b\u3057\u3066\u30ea\u30f3\u30d1\u7ba1\u306b\u6392\u6cc4\u3055\u308c\u308b\u306e\u304b\u3082\u660e\u3089\u304b\u306b\u306a\u3063\u3066\u304a\u3089\u305a <\/span><span style=\"color: #cf2d2d;\"><strong>(*8 Shindo, 2019)<\/strong><\/span><span style=\"font-weight: 400;\">\u3001\u4eca\u5f8c\u306e\u7814\u7a76\u304c\u671f\u5f85\u3055\u308c\u307e\u3059\u3002<\/span><\/p>\n<h2><b>\u5341\u5206\u306a\u7761\u7720\u6642\u9593\u306e\u78ba\u4fdd\u304c\u3001\u5065\u5eb7\u5897\u9032\u306b\u3064\u306a\u304c\u308b<\/b><\/h2>\n<p><span style=\"font-weight: 400;\">\u3053\u3053\u307e\u3067\u8ff0\u3079\u3066\u304d\u305f\u3068\u304a\u308a\u3001\u30a2\u30eb\u30c4\u30cf\u30a4\u30de\u30fc\u578b\u8a8d\u77e5\u75c7\u306e\u539f\u56e0\u306f\u3001\u30a2\u30df\u30ed\u30a4\u30c9\u03b2\u3084\u30bf\u30a6\u306a\u3069\u304c\u8133\u5185\u306b\u6c88\u7740\u3057\u8133\u795e\u7d4c\u7d30\u80de\u304c\u969c\u5bb3\u3055\u308c\u308b\u305f\u3081\u3068\u8003\u3048\u3089\u308c\u3066\u3044\u307e\u3059\u304c\u3001\u307e\u3060\u660e\u3089\u304b\u306b\u306a\u3063\u3066\u306f\u3044\u307e\u305b\u3093\u3002<br \/>\n\u307e\u305f\u3001\u8133\u5185\u306e\u8001\u5ec3\u7269\u3092\u9664\u53bb\u3059\u308b\u3068\u8a00\u308f\u308c\u3066\u3044\u308b\u30b0\u30ea\u30f3\u30d1\u30c6\u30a3\u30c3\u30af\u30b7\u30b9\u30c6\u30e0\u3082\u3001\u4eba\u9593\u306b\u304a\u3044\u3066\u306f\u78ba\u8a8d\u3055\u308c\u3066\u304a\u3089\u305a\u3001\u4eee\u8aac\u306e\u6bb5\u968e\u3067\u3059\u3002<\/span><\/p>\n<p><span style=\"font-weight: 400;\">\u3057\u304b\u3057\u3001\u9069\u5207\u306a\u7761\u7720\u304c\u4f55\u3089\u304b\u306e\u65b9\u6cd5\u3067\u8133\u5185\u306e\u8001\u5ec3\u7269\u3092\u9664\u53bb\u3059\u308b\u3053\u3068\u306f\u3001\u307b\u307c\u78ba\u5b9f\u3068\u8003\u3048\u3089\u308c\u3066\u3044\u307e\u3059\u3002<br \/>\n\u307e\u305f\u3001\u7761\u7720\u4e0d\u8db3\u304c\u3001\u8a8d\u77e5\u75c7\u3092\u306f\u3058\u3081\u3068\u3059\u308b\u5404\u7a2e\u75be\u60a3\u306e\u30ea\u30b9\u30af\u3092\u5897\u52a0\u3055\u305b\u308b\u3053\u3068\u3082\u660e\u3089\u304b\u306b\u306a\u3063\u3066\u3044\u307e\u3059\u3002<\/span><\/p>\n<p><span style=\"font-weight: 400;\">\u305f\u3060\u3057\u3001\u5fc5\u8981\u306a\u7761\u7720\u6642\u9593\u306f\u4eba\u306b\u3088\u3063\u3066\u7570\u306a\u308a\u307e\u3059\u3002<br \/>\n\u307e\u305f\u3001\u4e00\u822c\u7684\u306b\u306f\u52a0\u9f62\u306b\u4f34\u3063\u3066\u5fc5\u8981\u306a\u7761\u7720\u6642\u9593\u304c\u6e1b\u5c11\u3059\u308b\u305f\u3081\u3001\u5358\u7d14\u306b\u300c\u7761\u7720\u6642\u9593\u304c\u77ed\u3044\u3068\u8a8d\u77e5\u75c7\u306e\u30ea\u30b9\u30af\u304c\u9ad8\u307e\u308b\u300d\u3068\u3044\u3046\u308f\u3051\u3067\u306f\u306a\u3044\u3053\u3068\u306f\u899a\u3048\u3066\u304a\u304d\u307e\u3057\u3087\u3046\u3002<\/span><\/p>\n<p><span style=\"font-weight: 400;\">\u306a\u304a\u3001\u65e5\u4e2d\u306e\u6d3b\u52d5\u306b\u5f71\u97ff\u3059\u308b\u307b\u3069\u306e\u7720\u6c17\u304c\u306a\u3051\u308c\u3070\u3001\u591c\u9593\u306e\u7761\u7720\u6642\u9593\u304c\u77ed\u304f\u3066\u3082\u3001\u5341\u5206\u306a\u7761\u7720\u304c\u53d6\u308c\u3066\u3044\u308b\u3068\u5224\u65ad\u3067\u304d\u307e\u3059\u3002<br \/>\n\u9006\u306b\u3001\u8457\u3057\u3044\u65e5\u4e2d\u306e\u7720\u6c17\u304c\u3042\u308b\u5834\u5408\u306f\u3001\u7761\u7720\u4e0d\u8db3\u304c\u8003\u3048\u3089\u308c\u307e\u3059\u3002<br \/>\n\u5341\u5206\u306a\u7761\u7720\u6642\u9593\u3092\u78ba\u4fdd\u3057\u3001\u305d\u306e\u3046\u3048\u3067\u7720\u6c17\u304c\u7d9a\u304f\u5834\u5408\u306f\u3001\u300c\u904e\u7720\u75c7\u300d\u3084\u300c\u7761\u7720\u6642\u7121\u547c\u5438\u75c7\u5019\u7fa4\u300d\u306a\u3069\u306e\u7761\u7720\u75be\u60a3\u306e\u53ef\u80fd\u6027\u304c\u3042\u308b\u305f\u3081\u3001\u7761\u7720\u5916\u6765\u3067\u306e\u7cbe\u5bc6\u691c\u67fb\u304c\u671b\u307e\u308c\u307e\u3059\u3002<\/span><\/p>\n<p><b>\u3010\u53c2\u8003\u6587\u732e\u4e00\u89a7\u3011<\/b><\/p>\n<p><span style=\"color: #cf2d2d;\"><strong>\uff08*1\uff09<\/strong><\/span><span style=\"font-weight: 400;\">\u795e\u6797\u5d07\uff0c\u85e4\u539f\u6b63\u660e 2021. \u7761\u7720\u3068\u8001\u5316\u5236\u5fa1. <\/span><i><span style=\"font-weight: 400;\">\u6297\u52a0\u9f62\u30fb\u8001\u5316\u5236\u5fa1\u3000\u6700\u65b0\u533b\u7642\/\u30d3\u30b8\u30cd\u30b9\u7dcf\u89a7<\/span><\/i><span style=\"font-weight: 400;\">.<br \/>\n<\/span><span style=\"color: #cf2d2d;\"><strong>\uff08*2\uff09<\/strong><\/span><span style=\"font-weight: 400;\">MISHIMA, K. 2015. Sleep and sleep disorders in the elderly. <\/span><i><span style=\"font-weight: 400;\">Journal of the National Institute of Public Health,<\/span><\/i><span style=\"font-weight: 400;\"> 64, 27-32.<br \/>\n<\/span><span style=\"color: #cf2d2d;\"><strong>\uff08*3\uff09<\/strong><\/span><span style=\"font-weight: 400;\">OHAYON, M. M., CARSKADON, M. A., GUILLEMINAULT, C. &amp; VITIELLO, M. V. 2004. Meta-analysis of quantitative sleep parameters from childhood to old age in healthy individuals: developing normative sleep values across the human lifespan. <\/span><i><span style=\"font-weight: 400;\">Sleep, <\/span><\/i><span style=\"font-weight: 400;\">27, 1255-73.<br \/>\n<\/span><span style=\"color: #cf2d2d;\"><strong>\uff08*4\uff09<\/strong><\/span><span style=\"font-weight: 400;\">GULIA, K. K. &amp; KUMAR, V. M. 2018. Sleep disorders in the elderly: a growing challenge. <\/span><i><span style=\"font-weight: 400;\">Psychogeriatrics, <\/span><\/i><span style=\"font-weight: 400;\">18, 155-165.<br \/>\n<\/span><span style=\"color: #cf2d2d;\"><strong>\uff08*5\uff09<\/strong><\/span><span style=\"font-weight: 400;\">HUANG, Y., POTTER, R., SIGURDSON, W., SANTACRUZ, A., SHIH, S., JU, Y. E., KASTEN, T., MORRIS, J. C., MINTUN, M., DUNTLEY, S. &amp; BATEMAN, R. J. 2012. Effects of age and amyloid deposition on A\u03b2 dynamics in the human central nervous system. <\/span><i><span style=\"font-weight: 400;\">Arch Neurol,<\/span><\/i><span style=\"font-weight: 400;\"> 69, 51-8.<br \/>\n<\/span><span style=\"color: #cf2d2d;\"><strong>\uff08*6\uff09<\/strong><\/span><span style=\"font-weight: 400;\">NEDERGAARD, M. 2013. Neuroscience. Garbage truck of the brain. Science, 340, 1529-30.<br \/>\n<\/span><span style=\"color: #cf2d2d;\"><strong>\uff08*7\uff09<\/strong><\/span><span style=\"font-weight: 400;\">XIE, L., KANG, H., XU, Q., CHEN, M. J., LIAO, Y., THIYAGARAJAN, M., O&#8217;DONNELL, J., CHRISTENSEN, D. J., NICHOLSON, C., ILIFF, J. J., TAKANO, T., DEANE, R. &amp; NEDERGAARD, M. 2013. Sleep drives metabolite clearance from the adult brain. <\/span><i><span style=\"font-weight: 400;\">Science, <\/span><\/i><span style=\"font-weight: 400;\">342, 373-7.<br \/>\n<\/span><strong><span style=\"color: #cf2d2d;\">\uff08*8\uff09<\/span><\/strong><span style=\"font-weight: 400;\">SHINDO, A. 2019. Small vessel disease and Alzheimer&#8217;s disease ; the glymphatic pathway in amyloid beta clearance system.<\/span><i><span style=\"font-weight: 400;\"> Neurological Therapeutics, <\/span><\/i><span style=\"font-weight: 400;\">36, 524-527.<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u91d1\u6ca2\u533b\u79d1\u5927\u5b66 \u9ad8\u9f62\u533b\u5b66\u79d1 \u81e8\u5e8a\u51c6\u6559\u6388 \u5c0f\u91ce\u592a\u8f14 \u5148\u751f \u7b51\u6ce2\u5927\u5b66\u56fd\u969b\u7d71\u5408 [&hellip;]<\/p>\n","protected":false},"author":80,"featured_media":40612,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[75,43],"tags":[330,331],"class_list":["post-40617","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-doctors","category-interview","tag-d00042","tag-d00043"],"acf":[],"_links":{"self":[{"href":"https:\/\/www.mcsg.co.jp\/kentatsu\/wp-json\/wp\/v2\/posts\/40617","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.mcsg.co.jp\/kentatsu\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.mcsg.co.jp\/kentatsu\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.mcsg.co.jp\/kentatsu\/wp-json\/wp\/v2\/users\/80"}],"replies":[{"embeddable":true,"href":"https:\/\/www.mcsg.co.jp\/kentatsu\/wp-json\/wp\/v2\/comments?post=40617"}],"version-history":[{"count":4,"href":"https:\/\/www.mcsg.co.jp\/kentatsu\/wp-json\/wp\/v2\/posts\/40617\/revisions"}],"predecessor-version":[{"id":48488,"href":"https:\/\/www.mcsg.co.jp\/kentatsu\/wp-json\/wp\/v2\/posts\/40617\/revisions\/48488"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.mcsg.co.jp\/kentatsu\/wp-json\/wp\/v2\/media\/40612"}],"wp:attachment":[{"href":"https:\/\/www.mcsg.co.jp\/kentatsu\/wp-json\/wp\/v2\/media?parent=40617"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.mcsg.co.jp\/kentatsu\/wp-json\/wp\/v2\/categories?post=40617"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.mcsg.co.jp\/kentatsu\/wp-json\/wp\/v2\/tags?post=40617"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}